Reduction of capsular polysaccharide production in Klebsiella pneumoniae by sodium salicylate

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Reduction of capsular polysaccharide production in Klebsiella pneumoniae by sodium salicylate.

Heavily encapsulated Klebsiella pneumoniae (serotypes 1 and 2) was cultured in the presence of sodium salicylate. The addition of salicylate (2 to 30 micrograms/ml) progressively decreased the amount of capsular polysaccharide produced by all strains without significantly inhibiting cell growth. Further addition of salicylate (50 to 200 micrograms/ml) was progressively inhibitory to cell growth...

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ژورنال

عنوان ژورنال: Infection and Immunity

سال: 1989

ISSN: 0019-9567,1098-5522

DOI: 10.1128/iai.57.12.3778-3782.1989